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  • Title: The "pseudo-CSF" signal of orbital optic glioma on magnetic resonance imaging: a signature of neurofibromatosis.
    Author: Brodsky MC.
    Journal: Surv Ophthalmol; 1993; 38(2):213-8. PubMed ID: 8236001.
    Abstract:
    A five-and-a-half-year-old boy with neurofibromatosis had bilateral orbital optic gliomas visible on magnetic resonance imaging. Both tumors displayed a double-intensity signal characterized by a circumferential area of CSF-intensity tissue surrounding and sharply delimited from a central linear core of opposite signal intensity. The peripheral CSF-intensity signal in orbital optic glioma correlates with the histopathological finding of perineural arachnoidal gliomatosis and serves as a neuroradiologic marker for neurofibromatosis.
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