These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Caveolae: where incoming and outgoing messengers meet.
    Author: Anderson RG.
    Journal: Proc Natl Acad Sci U S A; 1993 Dec 01; 90(23):10909-13. PubMed ID: 8248193.
    Abstract:
    Plasmalemmal caveolae were first identified as an endocytic compartment in endothelial cells, where they appear to move molecules across the cell by transcytosis. More recently, they have been found to be sites where small molecules are concentrated and internalized by a process called potocytosis. A growing body of biochemical and morphological evidence indicates that a variety of molecules known to function directly or indirectly in signal transduction are enriched in caveolae. This raises the possibility that a third function for caveolae is to process hormonal and mechanical signals for the cell. Insights gained from studying potocytosis suggest several different ways that this membrane specialization might function to integrate incoming and outgoing cellular messages.
    [Abstract] [Full Text] [Related] [New Search]