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  • Title: [Action potential changes induced by a polyflavane on normal or hypoxic guinea pig myocardial strips].
    Author: Auclair MC, Lemeignan M, Rodallec A.
    Journal: C R Acad Hebd Seances Acad Sci D; 1976 Sep 27; 283(6):695-8. PubMed ID: 825319.
    Abstract:
    On normal isolated or stimulated Guinea-Pig myocardial strips, a polyflavane extracted from Poterium spinosum (Rosaceae) increased the duration of the action potential plateau phase. Such a modification was also elicited on hypoxic strips; in this case it did not depend on the glucose concentration in the medium; it could be related to an effect on the slow calcium-sodium channel.
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