These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Evaluation of the potential benefit of computer-aided diagnosis (CAD) for lung cancer screenings using photofluorography: analysis of an observer study].
    Author: Matsumoto T, Doi K, Kano A, Nakamura H, Nakanishi T.
    Journal: Nihon Igaku Hoshasen Gakkai Zasshi; 1993 Oct 25; 53(10):1195-207. PubMed ID: 8255750.
    Abstract:
    To evaluate the potential benefit of computer-aided diagnosis (CAD) in lung cancer screenings using photofluorographic films, we performed an observer test with 12 radiologists. We used 60 photofluorographic films obtained from a lung cancer screening program in Yamaguchi Prefecture (30 contained cancerous nodules and 30 had no nodules). In these cases, our current automated detection scheme achieved a sensitivity of 80%, but yielded an average of 11 false-positives per image. The observer study consisted of three viewing conditions: 1) only the original image (single reading), 2) the original image and computer output obtained from the current CAD scheme (CAD 1), 3) the original image and computer output obtained from a simulated improved CAD scheme with the same 80% true-positive rate, but with an average of one false-positive per image (CAD 2). Compared with double reading using independent interpretations, which is based on a higher score between two single readings, CAD 2 was more sensitive in subtle cases. The specificity of CAD was superior to that of double reading. Although CAD 1 (Az = 0.805) was inferior to double reading (Az = 0.837) in terms of the ROC curve, CAD 2 (Az = 0.872) significantly improved the ROC curve and also significantly reduced observation time (p < 0.05). If the number of false positives can be reduced, computer-aided diagnosis may play an important role in lung cancer screening programs.
    [Abstract] [Full Text] [Related] [New Search]