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  • Title: [Tetracycline pleurodesis in the treatment of spontaneous pneumothorax].
    Author: Olsen PS, Krasnik M, Andersen HO.
    Journal: Ugeskr Laeger; 1993 Oct 11; 155(41):3291-3. PubMed ID: 8256323.
    Abstract:
    From 1979 to 1988 483 patients were admitted with primary spontaneous pneumothorax. All patients underwent thoracoscopy to identify the cause of pneumothorax. Chemical pleurodesis with tetracycline was performed if cysts less than 2 cm in diameter were found. If larger cysts were found the patient underwent thoractomy. In 93 patients with cysts larger than 2 cm the recurrence rate after thoracotomy was 4%. In 390 patients treated with intrapleural instillation of tetracycline, the recurrence rate was 16% (61 patients). The cause of recurrence in 42 patients was cysts missed at the initial thoracoscopy. This study has demonstrated that thoracoscopy is a reliable and safe method for selection of patients for chemical pleurodesis.
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