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  • Title: Intracavernous papaverine for impotence in spinal cord injured patients.
    Author: Kapoor VK, Chahal AS, Jyoti SP, Mundkur YJ, Kotwal SV, Mehta VK.
    Journal: Paraplegia; 1993 Oct; 31(10):675-7. PubMed ID: 8259331.
    Abstract:
    The majority of the spinal cord injury patients in our centre are young healthy males aged between 20 and 40 years. Loss of erection and inability to have coitus and father children have been responsible for inadequate sociosexual rehabilitation. In 1985, under urologist supervision, intracavernosal papaverine injection treatment was started in 101 volunteers, 65 paraplegics and 36 tetraplegics. Satisfactory erection sufficient for coital penetration was possible in 98 patients. Three had prolonged erection lasting beyond 4 hours. Only one required irrigation of the corpus with saline to achieve detumscence. One patient developed cavernosal fibrosis necessitating discontinuing the injection. Administration was under medical supervision so that possible complications of priapism/systemic effects could be promptly managed.
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