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  • Title: First myocardial infarction in patients under 60 years old: the role of exercise tests and symptoms in deciding whom to catheterise.
    Author: Cross SJ, Lee HS, Kenmure A, Walton S, Jennings K.
    Journal: Br Heart J; 1993 Nov; 70(5):428-32. PubMed ID: 8260273.
    Abstract:
    OBJECTIVE: To determine the role of exercise tests and assessment of angina in the detection of potentially threatening disease in young patients with infarcts. DESIGN: Elective readmission of patients at a mean (SD) of 60 (30) days after acute myocardial infarction for assessment of angina, treadmill exercise tests, and cardiac catheterisation. SETTING: Cardiology department of a teaching hospital. PATIENTS: 186 consecutive survivors, aged under 60 years and discharged from the coronary care unit after a first myocardial infarction. MAIN OUTCOME MEASURES: Coronary arteriography, presence of angina, result of exercise tests, and referral for revascularisation. RESULTS: 31% of patients had either two vessel disease (with proximal left anterior descending involvement), three vessel disease, or left main stem disease. 49% of all patients had angina. Of the 173 patients who had an exercise test 34% had 1 mm and 24% had 2 mm of exercise induced ST depression. Thirty percent had no angina and a negative exercise test: after a mean (SD) follow up of 16 (4) months none of this symptom free sub-group had died, had experienced a further myocardial infarction, or had been referred for revascularisation. 79% of patients with either two vessel disease (with proximal left anterior descending involvement), three vessel disease, or left main stem disease had either angina or a 1 mm ST depression during the exercise test. CONCLUSION: Patients without cardiac pain after myocardial infarction and without ST changes during an exercise do not need arteriography.
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