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Title: Cytochemical studies on T and B lymphocytes and lymphoblasts with special reference to acid phosphatase. Author: Wehinger H, Möbius W. Journal: Acta Haematol; 1976; 56(3):129-36. PubMed ID: 826067. Abstract: Lymphoblasts from ten patients with ALL or stage IV malignant lymphoma were studied cytochemically and investigated for rosette-forming capacity with sheep red blood cells (SRBC) as a T cell surface marker. SRBC binding capacity and acid phosphatase or beta-glucuronidase were tested simultaneously in single lymphocytes isolated from normal blood donors. Our results suggest that the presence of acid phosphatase (and beta-glucuronidase) represents a functional state of lymphocytes or lymphoblasts qualitatively independent of T cell differentiation, but quantitatively more pronounced in T cells than in B lymphocytes or non-T lymphoblasts.[Abstract] [Full Text] [Related] [New Search]