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  • Title: [Involvement of the spleen in congenital osteopetrosis of the "op" rat: corrective effect of thymus grafts].
    Author: Graf B, Thillard MJ, Labat ML, Cros M, Milhaud G.
    Journal: C R Acad Hebd Seances Acad Sci D; 1976 Oct 18; 283(9):1073-6. PubMed ID: 826341.
    Abstract:
    In the osteopetrotic mutant rat "op", the white pulp of the spleen is poor in T lymphocytes, while the red pulp is hyperplastic in reaction to the aplastic bone marrow. Grafting of normal thymus into the mutant corrects these anomalies.
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