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  • Title: An approach to the determination of endotoxin in anesthetics and antibiotics: use of an ultrafiltration system and enzymatic LAL reaction.
    Author: Justicia H, Ibañez M.
    Journal: J Parenter Sci Technol; 1993; 47(5):205-10. PubMed ID: 8263660.
    Abstract:
    An ultrafiltration system is used to obtain an endotoxin-free buffer for the LAL test. The procedure is combined with a kinetic LAL reaction of high sensitivity. This approach allows for the easy determination of endotoxin levels in parenterals with LAL-interfering substances, reducing the maximum valid dilution necessary for use in product development.
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