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  • Title: [Thyroxine in the treatment of euthyroid goiter and the prevention of goiter recurrence].
    Author: Goebel R, Leb G, Pohl P, Haralambus I, Warnkross H.
    Journal: Acta Med Austriaca; 1976; 3(3):78-80. PubMed ID: 826506.
    Abstract:
    Patients with non-toxic goitre, or patients after an operation of non-toxic goitre, were given 75 mug thyroxine daily. The level of TSH decreased significantly only for the non-toxic goitre group. The TSH-TRH-test showed a high percentage of abnormal results, even after several months of treatment. An index for free thyroxine increased a little, but significantly. The neck sizes decreased only in the post-operative group significantly. The final scans showed a high percentage of goitres. 75 mug thyroxine is too small a dosage in these patients and 100 to 150 mug daily seem to be indicated in the above mentioned states.
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