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  • Title: An archaeal trkA homolog near dnaK and dnaJ.
    Author: Macario AJ, Dugan CB, Conway de Macario E.
    Journal: Biochim Biophys Acta; 1993 Dec 14; 1216(3):495-8. PubMed ID: 8268235.
    Abstract:
    The first trkA gene homolog in the phylogenetic domain Archaea is reported. The gene is located near the dnaK-dnaJ gene cluster in the genome of Methanosarcina mazei S-6, and encodes a protein homologous to the only other TrkA known, i.e., that of the bacterium Escherichia coli, involved in K+ transport. This finding supports an essential, evolutionarily early, and conserved role for this gene in cell survival and adaptation.
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