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  • Title: Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.
    Author: Inada A, Nakanishi T, Konoshima T, Kozuka M, Tokuda H, Nishino H, Iwashima A.
    Journal: Biol Pharm Bull; 1993 Sep; 16(9):930-1. PubMed ID: 8268862.
    Abstract:
    Two-stage carcinogenesis of mouse skin papillomas induced by 7,12-dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA), and mouse pulmonary tumors induced by 4-nitroquinoline-N-oxide (4NQO) and glycerol, were inhibited by digitoxin (1).
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