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  • Title: [Plasma level of complement fractions C3 and C4 in children with glomerular nephropathies. Correlations with morphological and immunopathological studies of renal biopsies].
    Author: Loirat C, Levy M.
    Journal: Arch Fr Pediatr; 1976 Nov; 33(G):853-72. PubMed ID: 827270.
    Abstract:
    The measurement of the plasmatic level of C3 may easily be included in the record of all glomerular nephropathies. Its decrease is an important argument for the diagnosis of post-infectious acute glomerulonephritis, or renal involvement in sepsis supervening to a ventriculo-atrial diversion. Variations of C3 level are of major importance in the management of the nephropathies in systemic lupus. Besides these special etiological circumstances, a persisting low level of C3 most often cooresponds to a membrano-proliferative glomerulonephritis especially of the type characterized by intra-membranous dense deposits.
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