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  • Title: [Portal venous thrombosis following splenectomy in portal hypertension: risks and management].
    Author: von Flüe M, Rothenbühler JM, Bianchi L, Pippert H, Beglinger C, Harder F.
    Journal: Schweiz Med Wochenschr; 1993 Dec 11; 123(49):2309-17. PubMed ID: 8272806.
    Abstract:
    Splenectomy intended to treat hypersplenism can, in the presence of portal hypertension (PTH), lead to extrahepatic portal and mesenteric vein thrombosis. The management of possible variceal bleeding in patients with extrahepatic portal vein occlusion following splenectomy in portal hypertension is a problematic and challenging undertaking. We report on the management of variceal bleeding in 2 noncirrhotic patients with PTH who developed portal vein thrombosis following ill-advised splenectomy. It must be stressed again that splenectomy alone intended to control hypersplenism in portal hypertension is to be avoided at all costs. Options for the treatment of portal and mesenteric vein thrombosis and variceal bleeding are proposed.
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