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  • Title: [Hypertension in patients with post-streptococcal glomerulonephritis].
    Author: Jovanović D, Bojanić N, Pantović R, Marić M, Skatarić V, Dimitrijević J.
    Journal: Vojnosanit Pregl; 1993; 50(4):343-8. PubMed ID: 8273303.
    Abstract:
    Sixty two patients with poststreptococcal glomerulonephritis (PSGN), aged 18-22 (mean = 19 +/- 0.5 years) were examined and treated at the Clinic of Nephrology of the M.M.A. from the beginning of 1986 to the end of 1990. Hypertension (diastolic pressure over 13 kPa, that is, 97.5 mmHg) in the acute phase was found in 59 (95.16%) patients, being of milder degree and short-term course. Transient increase of blood pressure required sometimes a short therapy (with furosemide mainly). With normalization of the glomerular filtration rate, withdrawal of edema, and normalization of the plasma volume, the blood pressure has been also normalized in the majority of patients (within 3-5 days). Observing PSGN evolution in the period from 2 to 5 years, hypertension was found in 3 (6.8%) of 44 patients. All three patients had the clear clinical evolution (proteinuria and erythrocyturia) without signs of renal insufficiency. The rebiopsy of the kidneys showed milder morphologic changes which were more manifested compared to the group without hypertension. Hypertension was present in the majority of patients in acute phase of PSGN while it was rarely found during the evolution of the disease and its presence has been poor prognostic sign in evolution since it contributed to development of glomerulosclerosis and later on renal insufficiency.
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