These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The crystal and molecular structure of trichosanthin at 2.6 A resolution.
    Author: Pan KZ, Lin YJ, Zhou KJ, Fu ZJ, Chen MH, Huang DR, Huang DH.
    Journal: Sci China B; 1993 Sep; 36(9):1069-81. PubMed ID: 8274201.
    Abstract:
    The crystallographic refinement of trichosanthin has been performed at 2.6 A resolution. The crystal and molecular structure of trichosanthin is described in detail in this paper. On summarizing the regularity of the amino acid sequences of eight kinds of ribosome inactivating proteins and combining with the crystal and molecular structure of trichosanthin, fifteen most conservative amino acid residues are analyzed. It is found that four most conservative polar amino acid residues Gln156, Glu160, Arg163 and Glu189 gather on the molecular surface on the boundary of the large and small domains, thus forming the active center of the protein molecule.
    [Abstract] [Full Text] [Related] [New Search]