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  • Title: The changing epidemiology of hepatitis A in Italy.
    Author: Stroffolini T, D'Amelio R, Matricardi PM, Chionne P, Napoli A, Rapicetta M, Crateri S, Pasquini P.
    Journal: Ital J Gastroenterol; 1993; 25(7):372-4. PubMed ID: 8280898.
    Abstract:
    In 1990, the prevalence of antibodies to hepatitis A virus infection (anti-HAV) was assayed by the ELISA method on a national sample of 1000 recruits aged 18-24 years. The overall prevalence was 29.4% (22.4% in the northern and central regions, 32.2% in the south and islands; p < 0.01). Compared with a similar study conducted in 1981, the results show a marked reduction in anti-HAV prevalence (from 66.3% to 29.4%; p < 0.01). These findings reflect the improved sanitation standards in Italy and indicate that the proportion of non-immune adults is increasing, with a higher risk of symptomatic infection in the near future.
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