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  • Title: The effects of a silica dentifrice containing Triclosan and zinc citrate on supragingival plaque and calculus formation and the control of gingivitis.
    Author: Svatun B, Saxton CA, Huntington E, Cummins D.
    Journal: Int Dent J; 1993 Aug; 43(4 Suppl 1):431-9. PubMed ID: 8282426.
    Abstract:
    A double blind, 7-month parallel clinical study was conducted to determine the effect of a dentifrice containing 0.3 per cent Triclosan and 0.75 per cent zinc citrate in a 0.8 per cent sodium monofluorophosphate/silica base on supragingival plaque, gingivitis and supragingival calculus formation, compared to a 0.8 per cent monofluorophosphate/silica control dentifrice. The results of this clinical study demonstrate that the use of the Triclosan/zinc citrate dentifrice over a 7-month period provided a statistically significant and clinically relevant benefit in controlling gingivitis, compared to a control dentifrice. Supragingival plaque and calculus levels were also significantly reduced in comparison to the effects of a control dentifrice.
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