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Title: Enhanced detection of brain tumors by [18F]fluorodeoxyglucose PET with glucose loading. Author: Ishizu K, Sadato N, Yonekura Y, Nishizawa S, Magata Y, Tamaki N, Tsuchida T, Okazawa H, Tanaka F, Miyatake S. Journal: J Comput Assist Tomogr; 1994; 18(1):12-5. PubMed ID: 8282860. Abstract: OBJECTIVE: We applied glucose loading during PET studies with [18F]2-fluoro-2-deoxy-D-glucose (FDG) to enhance detection of brain tumors by diminution of FDG uptake in normal gray matter. MATERIALS AND METHODS: This study involved three patients with glioblastomas. Two PET scans were performed in all cases within 1 week in control and with glucose loading state. RESULTS: In all patients, tumor was depicted more clearly with glucose loading than in the control study. The FDG uptake ratio of tumor to normal cortical gray matter showed a mean increase of 27% with glucose loading. CONCLUSION: This technique might be useful for detection of recurrent or residual tumors.[Abstract] [Full Text] [Related] [New Search]