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Title: Case report 797: "Dedifferentiated" lipoma-like liposarcoma of soft tissue with focal transformation to high-grade "sclerosing" osteosarcoma. Author: Ippolito V, Brien EW, Menendez LR, Mirra JM. Journal: Skeletal Radiol; 1993 Nov; 22(8):604-8. PubMed ID: 8291014. Abstract: We have presented the first case of a lipoma-like liposarcoma of the soft tissues with high-grade malignant transformation to a high-grade osteosarcoma, the latter component of which responded well to systemic chemotherapy. With 4 months of follow-up the patient is without evidence of disseminated disease. The various types of liposarcoma are listed and several described in some detail. Of particular importance is the potential for development of a highly malignant sarcoma from a relatively indolent low-grade liposarcoma, with even osteosarcoma developing.[Abstract] [Full Text] [Related] [New Search]