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Title: A novel quinone antibiotic from Malbranchea cinnamomea TAIM 13T54. Author: Chiung YM, Fujita T, Nakagawa M, Nozaki H, Chen GY, Chen ZC, Nakayama M. Journal: J Antibiot (Tokyo); 1993 Dec; 46(12):1819-26. PubMed ID: 8294239. Abstract: A novel quinone antibiotic named malbranicin was isolated from the culture filtrate and mycelium of Malbranchea cinnamomea TAIM 13T54, a thermophilic fungus. The antibiotic was elucidated to be 6-(1-acetylethyl)-2-methoxy-2,5-cyclohexadiene-1,4-dione by spectral analysis. Malbranicin exhibited antimicrobial and cytotoxic activities against Gram-positive bacteria and mammalian cell lines, respectively.[Abstract] [Full Text] [Related] [New Search]