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  • Title: [Combined chemotherapy of patients with tuberculosis - new regimens and dosage forms].
    Author: Sokolova GB, Koriakin VA, Khalbaeva IV, Elistratova NA, Ziia AV.
    Journal: Probl Tuberk; 1993; (5):21-3. PubMed ID: 8295879.
    Abstract:
    310 patients with pulmonary tuberculosis disseminating bacteria received isoniazid, rifampicin, streptomycin (ethambutol) and pirazinamid in different regimens and dosage forms. The drugs were administered in sequence or simultaneously, in single or divided doses. The best time and number characteristics as regards the discharge negativation were obtained in pirazinamid administration at a single dose daily or each other day irrespective of other drugs intake. 100 patients were given isoniazid, rifampicin and pirazinamid in multicomponent form tricox (Jemis, India). Tricox proved effective under additional administration of isoniazid in the same dose as was fixed in tricox.
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