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  • Title: Low predictive value of c-ANCA and anti-alpha-granule antibody for vasculitis in Hong Kong.
    Author: Lawton JW, Lee SS.
    Journal: Adv Exp Med Biol; 1993; 336():295-8. PubMed ID: 8296620.
    Abstract:
    One thousand sera, not previously tested for ANCA, were assayed for C-ANCA and anti-alpha-granule antibody. There was low concordance (23%) between the two assays in terms of positivity. Each assay gave a positive predictive value for systemic vasculitis excluding SLE and other connective-tissue diseases) of not more than 20%.
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