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  • Title: Correlation between the hypoosmotic swelling test and various sperm function tests.
    Author: Fuse H, Iwasaki M, Katayama T.
    Journal: Int J Fertil Menopausal Stud; 1993; 38(5):311-5. PubMed ID: 8298672.
    Abstract:
    OBJECTIVE: To compare the hypoosmotic swelling test (HOST) with other sperm function assays. MATERIALS AND METHODS: The HOST was performed on 105 patients with idiopathic infertility. The results were compared with those of various other sperm function tests, including the sperm penetration assay (SPA), triple-stain technique for evaluating acrosomal reactions, and the in vitro cervical mucus penetration test (Penetrak). RESULTS: A strong positive correlation was observed between percent sperm motility and the percent swollen sperm, between the motile sperm concentration and sperm swelling, and between sperm swelling and penetration values. Only a weak correlation was detected between sperm swelling and the percent sperm penetration. However, most of the cases with a sperm swelling percentage of 50% or more had good sperm penetration into ova. CONCLUSIONS: The HOST was useful to evaluate sperm tail function and was found valuable as a screening test prior to the SPA.
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