These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Clinical usefulness of thallium-201 chloride in the diagnosis of tumors (I)--Evaluation in brain tumors].
    Author: Endo K, Yui N, Suzuki K, Torizuka K.
    Journal: Kaku Igaku; 1994 Jan; 31(1):53-61. PubMed ID: 8309111.
    Abstract:
    Forty-eight patients with suspected brain tumor were studied to evaluate the clinical efficacy of Thallium-201 (201Tl) SPECT. 201Tl scintigrams showed abnormal accumulation in 24/26 (92.3%) and 9/14 (64.3%) of patients with malignant and benign tumors, respectively. 201Tl tended to be retained more prominently in malignant brain tumors than in benign ones. The lesion-to-normal ratios (L/N ratios) of 201Tl demonstrated significant correlation with those of 18F-FDG (n = 5, r = 0.90, p = 0.044). L/N ratios were higher in patients with recurrent tumors than those with necrotic lesions (3.33 +/- 0.81 and 1.73 +/- 0.81, respectively, p = 0.0123). The positive predictive value of L/N ratios > or = 2.5 for diagnosing as recurrence and L/N ratios < 2.5 as necrosis were 83.3% and 100%, respectively. These results suggest that 201Tl scintigraphy may be useful to determine the malignancy of brain tumors and to differentiate recurrence from necrosis after therapeutic procedures.
    [Abstract] [Full Text] [Related] [New Search]