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  • Title: Isolation and sequence of a full length cDNA encoding a novel rat inositol 1,4,5-trisphosphate 3-kinase.
    Author: Thomas S, Brake B, Luzio JP, Stanley K, Banting G.
    Journal: Biochim Biophys Acta; 1994 Jan 13; 1220(2):219-22. PubMed ID: 8312366.
    Abstract:
    Immunoscreening a rat liver cDNA expression library has led to the isolation of a full-length cDNA clone encoding a novel isoform of rat inositol 1,4,5-trisphosphate 3-kinase (IP3 3-kinase). Sequence comparison shows it (i) to be 93% identical to human hippocampus IP3 3-kinase B over 468 residues at the protein level, and (ii) to encode a protein 204 amino acids larger than the published sequence of its human homologue.
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