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  • Title: [Detection of human papillomavirus DNA and clinicopathological study of vulvar human papillomavirus infection].
    Author: Fan SR.
    Journal: Zhonghua Yi Xue Za Zhi; 1993 Oct; 73(10):590-2, 636-7. PubMed ID: 8313179.
    Abstract:
    We studied 217 vulvar HPV infection patients by clinically, pathologically, and virologically. From 90.6% of the cauliflower-like vulvar lesions and 29.7% of the papillomatous and finger-like lesions, we detected HPV 6/11 DNA by dot blotting hybridization. The patients in 90.0% of the cauliflower-like group and 9.8% of the papillomatous and finger-like group had a high risk factor to intercourse with different sex partners (P < 0.0001). The pathological characteristics, nature history, and response to treatment were different. According to clinical, pathological, and virological findings divided three types: vulvar HPV infection type 1 (or condylomata acuminata), vulvar HPV infection type 2, and vulvar HPV infection type 3.
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