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  • Title: Alpha interferon treatment of chronic hepatitis C in beta-thalassaemia.
    Author: Di Marco V, Lo Iacono O, Capra M, Grutta S, Ciaccio C, Gerardi C, Maggio A, Renda D, Almasio P, Pisa R.
    Journal: Gut; 1993; 34(2 Suppl):S142-3. PubMed ID: 8314484.
    Abstract:
    In this open, pilot study, interferon (IFN) alpha-2b seemed effective in the treatment of hepatitis C virus (HCV) infection in patients with beta-thalassaemia. In seven of nine patients who completed the study alanine aminotransferase activities returned to normal, and a completely stable response 24 months after treatment was seen in five. Liver biopsy specimen showed a clear reduction in portal, periportal, and lobular necroinflammation in all five cases. Three patients stopped treatment early because of side effects.
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