These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: High-speed automated discrete blood sampling for positron emission tomography.
    Author: Graham MM, Lewellen BL.
    Journal: J Nucl Med; 1993 Aug; 34(8):1357-60. PubMed ID: 8326399.
    Abstract:
    A computer controlled blood sampling system was designed specifically for rapid blood sampling for quantitative PET studies and uses solenoids that pinch silastic tubing, a roller pump and an inexpensive fraction collector. The controlling computer is an Apple II plus. The maximum sampling rate is one sample per 2 sec. Typical sample size is 0.90 +/- 0.02 g s.d. The loss of blood per sample is 2.6 ml. Tubing dead space is 1.2 ml. The response to a step change in activity between samples is 91% of the expected activity during high-speed sampling and 99% in the slower sampling mode. The major advantage of this device over flow-through detectors is that the blood is available for further processing to measure plasma or metabolite activities. This device has become a useful tool for quantitative PET studies, resulting in reliable sampling, lower radiation dose to personnel and fewer personnel necessary to conduct a study.
    [Abstract] [Full Text] [Related] [New Search]