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  • Title: [Hemodynamic effects and adverse effects of the anti-arrhythmic substance AWD-G256 in man].
    Author: Volkmann H, Dannberg G, Kühnert H, Hoffmann A, Marschner JP, Reimann I, Farker K.
    Journal: Pharmazie; 1993 May; 48(5):385-7. PubMed ID: 8327569.
    Abstract:
    In 19 patients with different supraventricular tachycardias the antiarrhythmic drug AWD-G256 was studied to investigate the effects on hemodynamic parameters. Over all, stroke volume, pulmonary pressure and systemic blood pressure were not significantly altered. The only main adverse effect was a transient rise of serum transaminases in two patients. We conclude that AWD-G256 is usually hemodynamically tolerated, but the antiarrhythmically effective dosage is not reached yet.
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