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  • Title: [CT and magnetic resonance imaging and spectroscopy for non-invasive study of regeneration of skeletal musculature after intensive therapy].
    Author: Bülow HH, Kanstrup L, Henriksen O, Ingemann-Jensen L, Qvist J.
    Journal: Ugeskr Laeger; 1993 Jul 19; 155(29):2273-6. PubMed ID: 8328098.
    Abstract:
    UNLABELLED: A 50 year old man was treated in the intensive care unit. Due to a prolonged catabolic state with a loss of 35 kg of body weight, he was practically paralyzed following 70 days of treatment. After 200 days of intensive physical training, he had recuperated remarkably. CT-scans before and after the physical training revealed 90-180% increase in the muscles examined. At the femoral level the muscle/fat ratio increased from 40% to 70%, indicating less atrophy. MR-imaging of the crural muscles showed a substantial increase in the muscle mass after training. MR-fat/water proton spectra showed a decrease in the relative fat content from 0.31 to 0.13 during training, objectively measuring the remission of the severe atrophy. CONCLUSION: CT- and MR-techniques can be used for objective, non-invasive, evaluations of muscle condition, and MR-proton spektroscopy can probably be used for following the remission of muscle atrophy during physical training.
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