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  • Title: Nucleolar changes in the oocytes of newborn rats treated with follicle stimulating hormone (FSH).
    Author: Csaba G, Madarász B.
    Journal: Cytobios; 1993; 74(296):7-14. PubMed ID: 8330488.
    Abstract:
    In the ovaries of newborn rats the exogenous follicle stimulating hormone (FSH) given in a large dose leads to the appearance of uncommon structures in the nucleoli of the oocytes. Fuzzy filaments sometimes with chiasma-like connections appear and ring-like structures in connection with, or independent of, the nucleoli are seen. The results demonstrate the possible appearance of a morphological response of oocytes to FSH prior to any detectable biochemical or receptor binding evidence.
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