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  • Title: Comparison of caudal morphine and buprenorphine for post-operative analgesia in children.
    Author: Girotra S, Kumar S, Rajendran KM.
    Journal: Eur J Anaesthesiol; 1993 Jul; 10(4):309-12. PubMed ID: 8330602.
    Abstract:
    Sixty five children aged from 1-10 years who underwent herniotomy, cystolithotomy or orchidopexy received either buprenorphine 4 micrograms kg-1 (n = 33) or morphine 50 micrograms kg-1 (n = 32) by the caudal epidural route; each thus received 0.5 ml kg-1 body weight. General anaesthesia was given for surgery. Post-operative pain and behaviour were assessed by an independent observer at 1, 4, 8, 16 and 24 h post-operatively. Caudal morphine and buprenorphine were equally effective for post-operative analgesia in children, but buprenorphine was better because of its longer duration of action and lower incidence of side effects.
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