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  • Title: [Intensive chemotherapy for alveolar soft part sarcoma with lung metastasis in a child].
    Author: Hibi S, Naya M, Takaya K, Morimoto M, Kataoka Y, Todo S, Imashuku S.
    Journal: Gan To Kagaku Ryoho; 1993 Jul; 20(9):1249-52. PubMed ID: 8333754.
    Abstract:
    Alveolar soft part sarcoma (ASPS) is one of the soft tissue sarcomas characterized by metastasis early in the course of the disease, regardless of slow tumor growth. The ultimate clinical outcome is, therefore, very poor. To date, the efficacy of combination chemotherapy for this tumor has not been confirmed. We present a case of ASPS in an 8-year-old boy with bilateral pulmonary metastasis who received systemic combination chemotherapy (CPM/IFO/ACD/ADR/CD DP/VP-16 as induction, and VCR/ACD as maintenance therapy) for eleven months. The result showed that despite the prevention of tumor progression, such intensive chemotherapy could not cure the disease. Besides refinement of chemotherapy regimens, immunotherapy might be considered for ASPS.
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