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  • Title: [Effect of verapamil with renal disease basic-prescription on hemorheology indexes of type II nephrotic syndrome].
    Author: Liang D, Li DD.
    Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi; 1993 Feb; 13(2):86-7, 68. PubMed ID: 8334344.
    Abstract:
    24 cases of type II nephrotic syndrome were studied and divided randomly into two groups. Group A: 12 cases treated with verapamil; Group B: 12 cases treated with verapamil plus Renal Disease Basic-prescription (RDBP). Hemorheology indexes were measured in the two groups before and 4 weeks after the treatment. The results showed hyperviscosity was obviously improved in group A after verapamil administration (P < 0.05), but the improvement in group B was much more significant than that in group A. The results mentioned above indicate that calcium channel blocker has an anticoagulant effect with inhibiting platelet aggregation, and Peach kernel, Safflower, etc of RDBP played a role in prohibiting platelets aggregation, anticoagulation and promoting microcirculation. However the combination of the two methods has better effect in improving the hypercoagulable state of nephrotic syndrome.
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