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  • Title: Effects of prindolol on impulse formation and conduction in man.
    Author: Di Biase M, Brindicci G, Rizzon P.
    Journal: J Electrocardiol; 1977 Jan; 10(1):45-50. PubMed ID: 833523.
    Abstract:
    Electrophysiologic changes produced by intravenous administration of 0.6 mg Prindolol were studied in 16 subjects with normal impulse formation and conduction. The most important changes were: sinus bradycardia, prolongation of atrial refractory periods, depression of intranodal conduction and prolongation of A-V node refractory periods. Sinus node recovery time was unchanged, and sinoatrial conduction time was only slightly increased. Intraventricular conduction time and the refractory period of the His-Purkinje system and of the bundle branches were unchanged.
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