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  • Title: Pulmonary cryptococcosis mimicking methotrexate pneumonitis.
    Author: Law KF, Aranda CP, Smith RL, Berkowitz KA, Ittman MM, Lewis ML.
    Journal: J Rheumatol; 1993 May; 20(5):872-3. PubMed ID: 8336316.
    Abstract:
    An 81-year-old man being treated with weekly low dose methotrexate (MTX) for psoriasis was admitted with a 2-month history of cough, shortness of breath and 7% eosinophilia in the peripheral blood. Chest roentgenogram revealed bilateral alveolar and interstitial infiltrates. Although the clinical presentation suggested MTX pneumonitis, a transbronchial lung biopsy established a diagnosis of pulmonary cryptococcosis. Pulmonary cryptococcosis should be included in the list of infectious processes that can mimic MTX pneumonitis.
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