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  • Title: Lytic antibody titre as a means of assessing cure after treatment of Chagas disease: a 10 years follow-up study.
    Author: Galvao LM, Nunes RM, Cançado JR, Brener Z, Krettli AU.
    Journal: Trans R Soc Trop Med Hyg; 1993; 87(2):220-3. PubMed ID: 8337734.
    Abstract:
    A complement-mediated lysis test (CoML) using living trypomastigotes was compared with conventional serological methods and with haemoculture. Over a 10 years follow-up period evidence was obtained which supported the view that chagasic patients, treated with nitroheterocyclic drugs, in whom CoML had reverted to negative, might be considered cured despite conventional serology remaining positive.
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