These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Quantification of the effects of fibrinolytic therapy upon the flow behavior of blood (author's transl)].
    Author: Schmid-Schönbein H, Rieger H, Hess H.
    Journal: Klin Wochenschr; 1977 Feb 01; 55(3):111-9. PubMed ID: 834021.
    Abstract:
    The effect of Streptokinase-infusion upon the flow properties of blood was investigated by viscometric and aggregometric methods. Under fibrinolytic therapy, we found in all cases a significant fall in fibrinogen content, as well as a strong reduction in plasma viscosity, velocity of red cell aggregate formation and shear resistance of red cell aggregates. In addition, a drop in apparent blood viscosity at all shear rates was found. In no case, a total desaggregation of red cell was noted. The hematocrit value remained practically constant; consequently, the drop in apparent blood viscosity at high (160 s-1) shear rates and intermediate (8 s-1) shear rates can be solely accounted for by the observed drop in plasma viscosity. At low shear rates (2.3 s-1) the observed drop in apparent viscosity is partly caused by aggregation desaggregation, but mainly by a drop in plasma viscosity. The presented results again confirm that the method of rotational viscometry only incompletely records the improvement in the flow properties of blood that are caused by a therapy aimed at a reduction of the plasma fibrinogen content.
    [Abstract] [Full Text] [Related] [New Search]