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  • Title: [Induction of synthesis of extracellular DNAase from Proteus mirabilis under the effect of compounds, blocking DNA replication].
    Author: Iusupova DV, Sanzhmiatavyn E, Sokolova RB, Petukhova EV.
    Journal: Mol Gen Mikrobiol Virusol; 1993; (3):36-9. PubMed ID: 8350881.
    Abstract:
    The effects of mitomycin C and nalidixic acid on the biosynthesis of extracellular endodeoxyribonuclease in Proteus mirabilis have been studied. The presence of both antibiotics in the periodic and short-time cultures of washed off cells has increased both the activity of the DNAse and protein yield in cultural liquid and bacterial cells. PAGE-electrophoresis has shown the effect of mitomycin C to increase or induce the synthesis a large number of Proteus mirabilis extracellular proteins.
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