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  • Title: Single-dose versus 3-day prophylaxis with ciprofloxacin in transurethral surgery. A clinical trial.
    Author: Bijl W, Janknegt RA.
    Journal: Urol Int; 1993; 51(2):73-8. PubMed ID: 8351758.
    Abstract:
    In 235 patients who underwent transurethral surgery, perioperative oral ciprofloxacin prophylaxis was given as a single dose 500 mg versus a 3-day regimen. Out of 180 evaluable patients, 84 received a single dose and 96 received a 3-day course. In the single dose prophylaxis group there were 5 failures and in the 3-day prophylaxis group there were 6 failures. The difference is not significant. In 17 patients whose urine culture preoperatively yielded microorganisms the 3-day prophylaxis significantly eradicated the bacteriuria in 83% of the patients.
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