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  • Title: [The DNA content of the neurons in the embryonic cerebellum transplanted into the cerebral cortex of adult rats].
    Author: Marshak TL, Kleshchinov VN, Brodskiĭ VIa.
    Journal: Ontogenez; 1993; 24(3):53-7. PubMed ID: 8355960.
    Abstract:
    Cerebellum of rat embryos at day 17 of gestation was transplanted into sensomotor cortex of adult syngenic rats. DNA content in granule and Purkinje cells of the transplant was determined cytophotometrically on day 30 after surgery. It is shown that granule cells are diploid; about 3% Purkinje cells contain hyperdiploid and tetraploid nuclei which corresponds to the content of such cells in the adult cerebellum. The conclusion is drawn that cell hyperploidy does not depend on the functional load but is essential property of the tissue.
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