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  • Title: Urinary excretion of beta2-microglobulin and other proteins in workers exposed to cadmium, lead or mercury.
    Author: Roels H, Bernard A, Buchet JP, Lauwerys, Masson P.
    Journal: Pathol Biol (Paris); 1978 Sep; 26(6):329-31. PubMed ID: 83575.
    Abstract:
    For the range of exposure to heavy metals sustained by the different groups of workers, a significant increase in the urinary excretion of low and/or high molecular weight proteins was found in the workers exposed to cadmium or to lead + cadmium, but no in those exposed to lead only and those exposed to mercury. Our observations suggest that the classical "tubular" proteinuria induced by cadmium has two not necessarily concomitant components : a "tubular type" component with increased excretion of low molecular weight proteins and a "glomerular type" component with increased excretion of high molecular weight proteins.
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