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Title: Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic. Author: Shindo K, Kamishohara M, Odagawa A, Matsuoka M, Kawai H. Journal: J Antibiot (Tokyo); 1993 Jul; 46(7):1076-81. PubMed ID: 8360102. Abstract: A new antitumor antibiotic vicenistatin was isolated from the culture broth of Streptomyces sp. HC34. The structure of vicenistatin was elucidated by NMR spectral analysis. Vicenistatin exhibited antitumor activity against human colon carcinoma Co-3 in the xenograft model.[Abstract] [Full Text] [Related] [New Search]