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  • Title: Solitary thyroid nodule in adult Ethiopian patients. Analysis and experience in management in a teaching hospital.
    Author: Mengistu M.
    Journal: Trop Geogr Med; 1993; 45(3):126-8. PubMed ID: 8362454.
    Abstract:
    Between February 1986 and January 1991, a total of 340 patients with thyroid diseases were seen; 115 (33.8%) had solitary nodules. Of the latter, 28 had toxic adenoma and 87 had euthyroid nodules (M:F = 0.14:7.21); the mean age for the non-toxic cases was 32.8 +/- 10.0 years and for the toxic cases, 40.2 +/- 15.2 years. Clinically, the toxic nodules were 0.5 to 6 cm in diameter, cystic in over 36% and firm in the rest; no regional lymph node enlargement was noted. Thyroid scan in 45 (52%) patients showed 38 'cold', 4 hypofunctioning and 3 hyperfunctioning nodules. Ultrasonography in 22 patients (25.3%) revealed 9 cystic and 13 solid nodules, consistent with the clinical finding. Fine needle aspiration biopsy (FNAB) in 61 patients (70.1%) showed 30 cystic, 15 benign, 2 follicular adenoma, 2 Hürtle cell adenoma, 1 papillary carcinoma and 1 thyroiditis. Ten patients were operated; histology confirmed the cytology diagnosis in all but 1 in whom the cytology was benign but histology showed papillary carcinoma. The fine needle aspiration was also useful in the treatment of cystic lesions; hence it should be adopted particularly in areas where there is bed shortage.
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