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  • Title: In vitro antibacterial activity and beta-lactamase stability of CP-70,429 a new penem antibiotic.
    Author: Minamimura M, Taniyama Y, Inoue E, Mitsuhashi S.
    Journal: Antimicrob Agents Chemother; 1993 Jul; 37(7):1547-51. PubMed ID: 8363389.
    Abstract:
    In in vitro susceptibility tests, the new penem CP-70,429 showed potent antibacterial activity against gram-positive and gram-negative bacteria except Pseudomonas aeruginosa and Xanthomonas maltophilia. CP-70,429 was stable to various types of beta-lactamases except for the enzyme from X. maltophilia and was 16- to 128-fold more active than the other compounds against beta-lactamase-producing strains of Enterobacter cloacae and Citrobacter freundii.
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