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  • Title: Radiation therapy of giant aggressive keratoacanthomas.
    Author: Goldschmidt H, Sherwin WK.
    Journal: Arch Dermatol; 1993 Sep; 129(9):1162-5. PubMed ID: 8363401.
    Abstract:
    BACKGROUND AND DESIGN: Giant aggressive keratoacanthoma is a rare destructive subset of keratoacanthoma that frequently involves the facial region, grows rapidly to a large size, and often recurs after surgical management. The effectiveness of ionizing radiation therapy was examined in a retrospective study involving 16 patients; 14 of the tumors had recurred after surgical therapy. RESULTS: All tumors resolved with satisfactory cosmetic results and without recurrence following a fractionated course of superficial radiation therapy. CONCLUSIONS: Radiation therapy is an effective therapeutic modality for giant aggressive keratoacanthomas.
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