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  • Title: Studies in ureteral regeneration: replacement of a large segment of ureter with an in situ pedicle graft of proximal ureter.
    Author: Mobley DF.
    Journal: Invest Urol; 1977 Jan; 14(4):269-73. PubMed ID: 836464.
    Abstract:
    The phenomenon of ureteral regeneration has been of interest to clinicians, anatomists, and physiologists for many years. The object of this investigation was to study the regeneration of a long pedicle graft of ureter. Regeneration of the pedicle graft over a stent took place in 4 to 5 weeks. At sacrifice 8 to 10 months postoperatively, 7 of 10 operations were completely successful with no evidence of hydronephrosis, obstruction, or pyelonephritis. Two animals exhibited slight dilation of the upper tracts, and one operation was a failure. It is evident from this study that a strip of ureter removed from the ureteral artery will regenerate over a stent in 4 to 5 weeks if the blood supply from the adjacent adventitia is left intact.
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