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  • Title: Heart failure: its progression and its therapy.
    Author: Sonnenblick EH, LeJemtel TH.
    Journal: Hosp Pract (Off Ed); 1993 Sep 15; 28(9):121-30. PubMed ID: 8366150.
    Abstract:
    The complex pathology that leads to heart failure has hampered the search for optimal therapy. Even so, ACE inhibitors have become a cornerstone of treatment. After an acute MI, the goal of ACE inhibition is to limit LV remodeling and progression to ischemic cardiomyopathy and congestive failure. In advanced failure, the goal is to reverse peripheral vascular changes and ameliorate symptoms.
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